The smart Trick of Conolidine That No One is Discussing
2.two]decane core and defining the geometry of the exocyclic double bond. The activation energies of development on the vinyl-gold intermediates were calculated and exposed a silyl enol ether having an unprotected indole moiety as an acceptable precursor for the Toste cyclization. This six-stage synthesis did not involve any nonstrategic redox mani